The Five Series Study: Mortality of Military Participants in by Institute of Medicine (U. S.), Medical Follow Up Agency

By Institute of Medicine (U. S.), Medical Follow Up Agency

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Extra resources for The Five Series Study: Mortality of Military Participants in U. S. Nuclear Weapons

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The committee's letter report to the Defense Nuclear Agency, this study's sponsor and the Department of Defense entity responsible for the NTPR program, describes the relevant limitations of the data for these purposes and suggests ways to create dose data that could be appropriate for epidemiologic use (IOM, 1995; reprinted in this report as Appendix A). FINDINGS AND DISCUSSION Veteran concern about radiogenic cancer was a major impetus for this research. That leukemia, the cancer most consistently linked with radiation, is fairly rare is fortunate.

Analyses based on the proportional hazards model involve direct comparisons of the participant and referent cohorts, whereas standardized mortality ratios involve comparison of each group, separately, with external population rates. , all major categories of deaths, and specific groupings of cancers) and possible differences in effect for participants of test series conducted at the Pacific Proving Ground (sea series) and participants at the Nevada Test Site (land series). The initial plan for this epidemiologic study included the use of individual-level radiation dose data, compiled and estimated by NTPR, to test for dose-response relationships indicative of radiation-caused adverse health effects.

Page breaks are true to the original; line lengths, word breaks, heading styles, and other typesetting-specific formatting, however, cannot be retained, and some typographic errors may have been accidentally inserted. Please use the print version of this publication as the authoritative version for attribution. xxxi THE FIVE SERIES STUDY—PREPUBLICATION COPY FOR PUBLIC RELEASE 11AM OCTOBER 20, 1999 TABLE D-7. Summary of Completeness of the NTPR Participant List as Indicated by Veteran Responses to MFUA Solicitations Published in Veterans Publications TABLE D-8.

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