The Comprehensive Sourcebook of Bacterial Protein Toxins, by Joseph E. Alouf, Daniel Ladant Ph.D, Michel R. Popoff D.V.M.

By Joseph E. Alouf, Daniel Ladant Ph.D, Michel R. Popoff D.V.M. Ph.D

The complete Sourcebook of Bacterial Protein pollution 4th variation, contains chapters written via the world over recognized and well-respected experts. This ebook includes chapters dedicated to person pollutants, in addition to chapters that think about the several purposes of those pollution. enormous growth has been made in figuring out the constitution, functionality, interplay and trafficking into cells, in addition to mechanism of motion of poisons. Bacterial pollution are excited by the pathogenesis of many micro organism, a few of that are answerable for critical illnesses in human and animals, yet is also used as instruments in phone biology to dissect mobile approaches or used as healing brokers. Novel recombinant pollutants are already proposed within the therapy of a few illnesses, in addition to new vaccines. however, sure pollutants also are regarded as organic guns or bioterrorism threats. Given the multifaceted features of toxin study and the multidisciplinary methods followed, pollutants are of significant curiosity in lots of clinical components from microbiology, virology, telephone biology to biochemistry and protein constitution. This new version is written with a multidisciplinary viewers in brain and comprises five new chapters that mirror the most recent learn during this region. different chapters were mixed, deleted and completely revised as essential to bring appropriate and worthwhile content.

  • Descriptions of proper pollution in addition to consultant pollutants of the most bacterial toxin households to permit for a greater comparability among them.
  • Focused chapters on toxin functions and customary houses or normal good points of toxins.

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Additional resources for The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition

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Bacillus anthracis pXO1 plasmid sequence conservation among closely related bacterial species. J Bacteriol 2002;184:134–41. [240] Hu X, Van der Auwera G, Timmery S, Zhu L, Mahillon J. Distribution, diversity, and potential mobility of extrachromosomal elements related to the Bacillus anthracis pXO1 and pXO2 virulence plasmids. Appl Environ Microbiol 2009;75:3016–28. [241] Kiel JL, Parker JE, Holwitt EA, McCreary RP, Andrews CJ, De Los Santos A, et al. Geographical distribution of genotypic and phenotypic markers among Bacillus anthracis isolates and related species by historical movement and horizontal transfer.

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Importance of prophages to evolution and virulence of bacterial pathogens. Virulence 2013;4:354–65. [9] Popoff MR, Bouvet P. Genetic characteristics of toxigenic Clostridia and toxin gene evolution. Toxicon 2013;75:63–89. [10] Dover N, Barash JR, Hill KK, Davenport KW, Teshima H, Xie G, et al. Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5. PLoS One 2013;8:e61205. [11] Dover N, Barash JR, Hill KK, Xie G, Arnon SS. Molecular characterization of a novel botulinum neurotoxin type H gene.

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