MRSA (Methicillin-Resistant Staphylococcus aureus) by John A. Weigelt

By John A. Weigelt

Responding to the turning out to be problem in regards to the elevated frequency and resistance of MRSA infections, this valuable resource analyzes the most recent advancements within the id, evaluate, and administration of methicillin-resistant Staphylococcus aureus (MRSA) via top gurus at the subject.

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Additional info for MRSA (Methicillin-Resistant Staphylococcus aureus)

Example text

Hospitalization is rarely indicated if the correct diagnosis is made and the patient has no systemic signs of toxicity. PREVENTION Standard infection control principles are the best method to prevent outbreaks due to CA-MRSA. These include hand washing, daily showers, use of antibacterial soap, covering any draining lesions, isolation of infected patients needing hospitalization, and avoidance of sharing personal items. Isolation may require withholding athletes with draining wounds from competition, and not allowing healthcare workers with open wounds to return to work until they have healed (14).

It should be noted that this recommendation is based solely on in vitro toxin suppression data, extrapolation from experimental necrotizing infections caused by Group A streptococcus and Clostridium perfringens (Clostridium and GAS models), retrospective analysis, and recently case reports. The true pathogenesis of necrotizing fasciitis and necrotizing pneumonia has not been elucidated, but is associated with CAMRSA strains producing the Panon-Valentine leukocidin. Whether that toxin singly or in combination with other toxins is responsible is being actively studied.

Harbarth S, Sax H, Fankhauser-Rodriguez C, et al. Evaluating the probability of previously unknown carriage of MRSA at hospital admission. Am J Med 2006; 119:275 e15–e23. 30. Muto CA, Jernigan JA, Ostrowsky BE, et al. SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and enterococcus. Infect Control Hosp Epidemiol 2003; 24:362 – 386. 31. O’Grady NP, Alexander M, Dellinger EP, et al. Guidelines for the prevention of intravascular catheter-related infections.

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