Melatonin: Biological basis of its function in health and by S.R. Pandi-Perumal

By S.R. Pandi-Perumal

Show description

Read Online or Download Melatonin: Biological basis of its function in health and disease PDF

Best endocrinology books

Basic Medical Endocrinology, Third Edition

Uncomplicated clinical Endocrinology, 3rd version presents updated insurance of quickly unfolding advances within the realizing of hormones excited by regulating such a lot facets of physically services. The dialogue makes a speciality of molecular and mobile points of hormone creation and motion firmly rooted within the context of integrative body structure.

The Local Cardiac Renin-Angiotensin Aldosterone System

Until eventually lately, the renin-angiotensin-aldosterone process has been thought of a systemic endocrine hormonal procedure completely. it's referred to now that every section of the renin-angiotensin approach is produced, synthesized and certainly, found in many organisms together with the center and vessels. This quantity offers the newest scientific and laboratory stories of the prime physicians and investigators within the box of the neighborhood cardiac renin-angiotensin aldosterone approach.

Dietary Magnesium: New Research

Magnesium is the fourth such a lot considerable mineral within the physique and is vital to sturdy health and wellbeing. nearly 50 in line with cent of overall physique magnesium is located in bone. the opposite part is located predominantly within cells of physique tissues and organs. just one consistent with cent of magnesium is located in blood, however the physique works very not easy to maintain blood degrees of magnesium consistent.

Additional resources for Melatonin: Biological basis of its function in health and disease

Example text

At a concentration (500 µM) that greatly exceeded that of melatonin, ascorbate was less effective in limiting the cardiac arrhythmias induced by I/R. 21 Also using the isolated rat heart model, the addition of melatonin to the reperfusion medium (after a 30 min ischemic episode) was found to decrease ventricular tachycardia and VF relative to their frequencies in the hearts that were only subjected to I/R. , left ventricular pressure, were also improved as a consequence of melatonin administration.

Gastroprotective effect of melatonin and its precursor, L-tryptophan, against stress-induced and ischemia-induced lesions is mediated by scavenging of oxygen free radicals. Scand J Gastroenterol 1997; 32:433-438. 56. Brzozowski T, Konturek PC, Konturek SJ et al. The role of melatonin and L-tryptophan in prevention of acute gastric lesions induced by stress, ethanol, ischemia and aspirin. J Pineal Res 1997; 23:79-89. 57. Cuzzocrea S, Costantino G, Mazzon E et al. Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion.

Oxidative damage to the liver induced by ischemia-reperfusion: Protection by melatonin. Hepatogastroenterology 1996; 43:898-905. 53. de la Lastra CA, Cabeza J, Motilva V et al. Melatonin protects against gastric ischemia-reperfusion in rats. J Pineal Res 1997; 23:47-52. Melatonin and Ischemia-Reperfusion Injury 25 54. Konturek PC, Konturek SJ, Majka J et al. Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects.

Download PDF sample

Rated 4.85 of 5 – based on 34 votes