By John G. Gruhn (auth.), Jay J. Gold M.D., F.A.C.P, John B. Josimovich M.D. (eds.)
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Uncomplicated scientific Endocrinology, 3rd variation offers up to date assurance of quickly unfolding advances within the realizing of hormones fascinated by regulating so much elements of physically features. The dialogue makes a speciality of molecular and mobile elements of hormone creation and motion firmly rooted within the context of integrative body structure.
Until eventually lately, the renin-angiotensin-aldosterone method has been thought of a systemic endocrine hormonal process solely. it truly is referred to now that every part of the renin-angiotensin procedure is produced, synthesized and certainly, found in many organisms together with the guts and vessels. This quantity offers the newest medical and laboratory reviews of the best physicians and investigators within the box of the neighborhood cardiac renin-angiotensin aldosterone procedure.
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This effect of odor on the neuroendocrine system is brought about by pheromones. These chemical substances, detected by olfactory 2 I The Neuroendocrine System 19 neurons, are present in various bodily secretions such as urine, perspiration, and saliva. Other factors, such as stress, social interaction, and fear, alter pituitary function via the production of neurotransmitters and other neuropeptides. For example, pain can cause release of endorphins in the CNS. These endorphins bind to opiate receptors in the hypothalamus resulting in the release of PRL and GH and the suppression ofTSH and gonadotropin release.
Adams JH, Daniel PM, Pritchard MD: Transection of the pituitary stalk in man. Anatomical changes in the pituitary gland. J Neurol Neurosurg Psychiatry 29:545-555, 1966 4. Everett JW, Nikitovich-Winer M: Physiology of the pituitary gland as affected by transplantation or stalk section, in Nalbandov, AV (ed): Advances in Neuroendocrinology. Urbana, University of Illinois Press, 1963, pp 289-313* 5. Guillemin R: Peptides in the brain: The new endocrinology of the neuron. Science 202:390-402, 1978 6.
3. Releasing and inhibiting factors must alter the synthesis and/or release of the anterior pituitary hormones using an assay that has been proved not to respond to nonspecific stimuli. 4. Releasing and inhibiting factors should be effective in vivo when applied directly to the anterior pituitary. Care must be taken that the administered factors do not reach the hypothalamus. 5. Releasing and inhibiting factors should be detectable in hypophyseal portal blood. Moreover, changes in the concentration of these factors in the portal blood must result in concomitant changes in secretion of the anterior pituitary hormones.