Essential Human Virology by Jennifer Louten

By Jennifer Louten

Crucial Human Virology is written for the undergraduate point with case stories built-in into each one bankruptcy. The constitution and category of viruses can be coated, in addition to virus transmission and virus replication thoughts established upon form of viral nucleic acid. numerous chapters will concentrate on outstanding and recognizable viruses and the ailments because of them, together with influenza, HIV, hepatitis viruses, poliovirus, herpesviruses, and rising and unsafe viruses. also, how viruses reason sickness, or pathogenesis, may be highlighted through the dialogue of every virus family members, and a bankruptcy at the immune reaction to viruses might be integrated. additional, learn laboratory assays and viral prognosis assays might be mentioned, as will vaccines, anti-viral medicines, gene treatment, and the invaluable makes use of of viruses. via targeting common virology ideas, present and destiny applied sciences, popular human viruses, and the results of those viruses on people, this textbook will supply a pretty good origin in virology whereas conserving the curiosity of undergraduate scholars.

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A number of viruses also interfere with the stages of the cell cycle to increase the efficiency of virus replication. 4 THE CENTRAL DOGMA OF MOLECULAR BIOLOGY: DNA REPLICATION DNA replication, which occurs during S phase of the cell cycle, is the first tenet of the Central Dogma of Molecular Biology: DNA is replicated in the nucleus to create a copy of the DNA, DNA is transcribed into messenger RNA in the nucleus, and messenger RNA is translated by ribosomes in the cytosol to create a protein (Fig.

There are two broad categories of endocytosis: bulk-phase endocytosis and receptor-mediated endocytosis. In bulk-phase endocytosis, the cell forms a vesicle that engulfs whatever molecules are present in the extracellular fluid, and so the process is nonspecific. On the other hand, receptor-mediated endocytosis is initiated when specific ligands bind to receptors that are present on the cell surface. The cell has receptors on its surface for many biological factors, including growth factors and hormones.

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