By T. Ramamurthy, S.K. Bhattacharya
Though cholera is an old affliction, its perennial prevalence in numerous components of the realm has attracted many researches to discover methods and ability to wrestle the sickness. the present 7th pandemic cholera is dominating for the reason that 1961, however the size of the sickness has taken numerous silhouettes, because the genetic constitution and features of the Vibrio cholerae has replaced to an exceptional quantity. a number of fresh experiences have proven that transformation of the pathogen on the molecular point has ameliorated numerous cholera outbreaks and epidemics of with successive new clones of V. cholerae. This complete compilation, written through eminent overseas researchers studies the epidemiology of cholera in Africa, Asia, Russia and Latin Americas. the opposite chapters contributed through acclaimed authors hide quite a few elements on evolution, polysaccaharide biosynthesis, SXT aspect, integrons, small molecule signalling platforms, flagellar synthesis, filamentous phages, pathogenic function of proteases and hemolysin, and different putative virulence elements. furthermore, ecology of V. cholerae and administration of cholera have been additionally mentioned intimately. This e-book may be reliable resource of knowledge to all researchers with pursuits in infectious ailments, microbiology and molecular biology.
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Extra info for Epidemiological and Molecular Aspects on Cholera
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Several efficient methods in managing cholera outbreaks have been implemented in rural and urban areas after rigorous efficacy studies including introduction of new oral vaccines, supply of safe drinking water, sanitation, and timely administration of ORS. Success of these interventions depends on maintenance and regular practice at the community level. References 1. Barua, D. History of cholera. 1992. In: Barua CD, Greenough III WB, editors. Cholera New York, USA: Plenum Pub. Co. pp. 1–35. 2. Datta KK, Singh J.