By Stephen S. Morse
New epidemics akin to AIDS and "mad cow" affliction have dramatized the necessity to discover the standards underlying quick viral evolution and rising viruses. This accomplished quantity is the 1st to explain this multifaceted new box. It locations viral evolution and emergence in a historic context, describes the interplay of viruses with hosts, and info the advances in molecular biology and epidemiology that experience supplied the instruments essential to tune constructing viral epidemics and to become aware of new viruses way more effectively than may be performed within the fresh prior. This targeted ebook additionally lucidly information case histories and gives useful feedback for the prevention of destiny epidemics. The participants are prime gurus of their disciplines, and have been chosen either for his or her specialist wisdom and for his or her skill to outline and elucidate the elemental concerns. The e-book is very available and has been written for a large viewers that incorporates virologists, public overall healthiness professionals, scientific anthropologists, evolutionary biologists, geneticists, infectious ailment experts, and social scientists drawn to scientific and overall healthiness concerns.
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Extra resources for Emerging Viruses
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Borrow, E. A. Oldstone (1991). Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence. J. Virol. 65:1863-1869. , and E. Naylor (1988). Fish farming and influenza pandemics. Nature 331:215. M. Boyt (1990). Caliciviruses of ocean origin: A review. J. Zoo Wildl. Med. 21:3-23. Wellmer, H. (1983). Some reflections on the ecology of dengue hemorrhagic fever in Thailand.
Since roseola has been known since at least 1910 (Zahorsky, 1910), HHV-6 is likely to have been common for at least decades, and probably much longer. A related category is the association of some infectious agents with chronic diseases, such as the long established association of chronic hepatitis B infection and hepatocellular carcinoma. , 1991). As with roseola, the disease (in this case, gastric ulcers) was known for a long time but the identification of the putative cause is quite recent. Conceivably, on occasion, a change in the microbe or (more frequently) in host nutritional or immune status might result in a new or more serious disease.