Comprehensive Gynecology by Rogerio A. Lobo MD, David M Gershenson MD, Gretchen M Lentz

By Rogerio A. Lobo MD, David M Gershenson MD, Gretchen M Lentz MD, Fidel A Valea MD

The fundamental gynecology textual content for over 25 years, Comprehensive Gynecology covers all the key issues citizens, experts, basic care medical professionals, and different healthcare companies come across in daily perform. This seventh version has been fully up to date to incorporate a wealth of latest content, together with present discussions of minimally invasive surgical ways to gynecologic care, infertility concerns and coverings, successfully handling menopausal sufferers, and extra. Written in a transparent, concise and evidence-based style, it bargains the sensible, in-depth insurance you want to stay on the leading edge of your field.

  • Grasp key details quickly and simply through transparent writing, a medical concentration, and assistance on evidence-based techniques.
  • Access state-of-the-art information at the most up-to-date purposes in diagnostic and interventional ultrasound and different crucial features of modern-day practice.
  • Prepare for the demanding situations you could face with a criminal bankruptcy containing actual scenarios.

  • Expert seek advice e-book model integrated with buy. This more desirable booklet event allows you to look all the textual content, figures, photos, movies, and references from the booklet on quite a few units.
  • New movies, 20 in all, address subject matters reminiscent of Pap Smear recommendations; Hysteroscopic Metroplasty; Endometriosis of the Bladder; and more.
  • Explore very important matters in infertility, such as egg freezing, melanoma therapy, and preimplantation genetic diagnosis.
  • Understand the newest learn in menopause, how to successfully prescribe remedies, and the honour of utilizing hormones for prevention.
  • A new bankruptcy dedicated to in vitro fertilization retains you present with modern contemporary advances.
  • Updated Preoperative Care and Quality bankruptcy represents the continued 'Enhanced restoration after Surgery' care programs.

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Example text

The SRY gene on the Y chromosome is responsible for the development of testes. Without the presence of this gene, the gonadal development is ovarian. With the absence of Sertoli cells, AMH is not produced, the paramesonephric duct system develops into a phenotypic female configuration, and the mesonephric duct system is suppressed. The genital tubercle elongates to form the penis in the male and the clitoris in the female. Two functional X chromosomes are necessary for optimal development of the ovary.

In contrast to Mendel’s hypothesis that the phenotype of a gene is no different if inherited from the mother or the father, we now understand that there is a group of diseases in which the parent of origin of a gene or chromosome plays a role in the phenotype of the affected individual. The best-­studied example of this mechanism is Prader-Willi syndrome (PWS) and Angelman syndrome (AS). Both diseases arise from loss of function of the same gene on chromosome 15, but two different disease phenotypes arise depending on which parental allele is affected.

Differences between male and female embryos can be noted as early as the ninth week, but the distinct final forms are not noted until 12 weeks’ gestation (Fig. 15). The phallus grows in length to form a penis, and the urogenital folds are pulled forward to form the lateral walls of the urethral groove on the undersurface of the penis. These folds then fuse to form the penile urethra. Defects in fusion of various amounts give rise to various degrees of hypospadias. The skin at the distal margin of the penis grows over the glans to form the prepuce (foreskin).

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