By Thomas Seyfried
The ebook addresses controversies regarding the origins of melanoma and gives ideas to melanoma administration and prevention. It expands upon Otto Warburg's recognized idea that every one melanoma is a affliction of power metabolism. even though, Warburg didn't hyperlink his thought to the "hallmarks of melanoma" and hence his concept was once discredited. This ebook goals to provide evidence, via case studies, that melanoma is essentially a metabolic sickness requring metabolic recommendations for its administration and prevention. aid for this place is derived from severe evaluation of present melanoma theories. mind melanoma case reports are provided as an explanation of precept for metabolic suggestions to sickness administration, yet similarities are interested in different forms of melanoma, together with breast and colon, because of the same cellular mutations that they exhibit.
Chapter 1 pictures of melanoma (pages 1–14):
Chapter 2 Confusion Surrounds the starting place of melanoma (pages 15–29):
Chapter three melanoma versions (pages 31–46):
Chapter four Energetics of standard Cells and melanoma Cells (pages 47–72):
Chapter five respiration disorder in melanoma Cells (pages 73–105):
Chapter 6 The Warburg Dispute (pages 107–117):
Chapter 7 Is respiratory common in melanoma Cells? (pages 119–132):
Chapter eight Is Mitochondrial Glutamine Fermentation a lacking hyperlink within the Metabolic thought of melanoma? (pages 133–144):
Chapter nine Genes, breathing, Viruses, and melanoma (pages 145–176):
Chapter 10 respiration Insufficiency, the Retrograde reaction, and the starting place of melanoma (pages 177–194):
Chapter eleven Mitochondria: the final word Tumor Suppressor (pages 195–205):
Chapter 12 Abnormalities in progress keep watch over, Telomerase job, Apoptosis, and Angiogenesis associated with Mitochondrial disorder (pages 207–213):
Chapter thirteen Metastasis (pages 215–252):
Chapter 14 Mitochondrial respiration disorder and the Extrachromosomal starting place of melanoma (pages 253–259):
Chapter 15 not anything in melanoma Biology is sensible other than within the mild of Evolution (pages 261–275):
Chapter sixteen melanoma remedy innovations (pages 277–289):
Chapter 17 Metabolic administration of melanoma (pages 291–354):
Chapter 18 sufferer Implementation of Metabolic remedies for melanoma administration (pages 355–373):
Chapter 19 melanoma Prevention (pages 375–386):
Chapter 20 Case reviews and private stories in utilizing the Ketogenic vitamin for melanoma administration (pages 387–403):
Chapter 21 Conclusions (pages 405–408):
Read Online or Download Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer PDF
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Additional info for Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer
Source: Reprinted with permission from Gupta and Sarin (23). See color insert. 12 Chapter 1 Images of Cancer David Servan-Schreiber (“Anticancer: A New Way of Life”) (24) and Siddhartha Mukherjee (“The Emperor of All Maladies: A Biography of Cancer”) (25). Synopsis The images of cancer have changed little for more than a hundred years. If anything, they have become worse in this new century. 1 show that we are not winning the war on cancer, regardless of what the pundits say (8). The promises of new drugs based on improved understanding of cancer genetics and biology have not materialized (26–28).
The chemical in the syringe is Adriamycin (doxorubicin), which Pope received along with other drugs during his battle with cancer. In this painting, Pope depicts an older woman with lymphatic cancer who is getting chemotherapy. The woman is wearing a turban to hide her baldness caused from the drug treatments. Pope attempts to convey the patient’s thoughts about the drug. The drug within the syringe elicits thoughts of either life or alarm. According to Pope, the painting shows the human encounter with poisonous drug therapy, an all-too-familiar scene for the cancer patient.
Servan-Schreiber D. Anticancer: A New Way of Life. New York: Viking; 2009. 25. Mukherjee S. The Emperor of all Maladies: A Biography of Cancer. New York: Scribner; 2010. 14 Chapter 1 Images of Cancer 26. Hambley TW, Hait WN. Is anticancer drug development heading in the right direction? Cancer Res. 2009;69:1259–62. 27. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–74. 28. Gibbs JB. Mechanism-based target identiﬁcation and drug discovery in cancer research.